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Endocrine Abstracts

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ea0099oc9.4 | Oral Communications 9: Pituitary and Neuroendocrinology | Part II | ECE2024

Kisspeptin administration does not alter anxiety or circulating cortisol levels in humans

Mills Edouard G , Thurston Layla , Yang Lisa , Suladze Sofiya , Hunjan Tia , Phylactou Maria , Patel Bijal , Clarke Sophie A. , Shah Amar J. , Izzi-Engbeaya Chioma , Tsoutsouki Jovanna , Bech Paul , Ertl Natalie , Demetriou Lysia , Wall Matthew B. , Goldmeier David , Abbara Ali , Comninos Alexander N. , Dhillo Waljit S.

Background: The neuropeptide kisspeptin is a key endogenous activator of the reproductive system. Due to its crucial role in modulating reproductive and behavioural processes, there has been accelerating interest in targeting kisspeptin-pathways to treat reproductive and psychosexual disorders. However, contradictory pre-clinical data from animal models suggests that kisspeptin can have an anxiolytic, anxiogenic or have no effects on anxiety. Given the rapid development of kis...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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